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1

Pharmacokinetics of Budesonide (Entocort™ EC) Capsules for Crohn’s Disease

Dr Staffan Edsbäcker, Tommy Andersson

Journal:

Clinical Pharmacokinetics

Year:

2004

Language:

english

File:

PDF, 197 KB

english, 2004

2

Folding of Aquaporin 1: Multiple evidence that helix 3 can shift out of the membrane core

Virkki, Minttu T., Agrawal, Nitin, Edsbäcker, Elin, Cristobal, Susana, Elofsson, Arne, Kauko, Anni

Journal:

Protein Science

Year:

2014

Language:

english

File:

PDF, 681 KB

english, 2014

3

Relationship between lung tissue and blood plasma concentrations of inhaled budesonide

J. M. M. Van Den Bosch, C. J. J. Westermann, J. Aumann, S. Edsbácker, M. Tönnesson, O. Selroos

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 237 KB

english, 1993

4

The use of on-line liquid chromatography/mass spectrometry and stable isotope techniques for the identification of budesonide metabolites

Claes Lindberg, Jan Paulson, Staffan Edsbäcker

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1987

Language:

english

File:

PDF, 587 KB

english, 1987

5

Pharmacokinetics and systemic activity of fluticasone via Diskus® and pMDI, and of budesonide via Turbuhaler®

Lars Thorsson, Staffan Edsbäcker, Anders Källén, Claes-Göran Löfdahl

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 156 KB

english, 2001

6

A cortisol suppression dose–response comparison of budesonide in controlled ileal release capsules with prednisolone

Edsbäcker, Nilsson, Larsson

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 226 KB

english, 1999

7

Effect of food on the pharmacokinetics of budesonide controlled ileal release capsules in patients with active Crohn’s disease

P. Lundin, T. Naber, M. Nilsson, S. Edsbäcker

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2001

Language:

english

File:

PDF, 242 KB

english, 2001

8

Pharmacokinetics of budesonide controlled ileal release capsules in children and adults with active Crohn's disease

P. D. P. Lundin, S. Edsbäcker, M. Bergstrand, J. Ejderhamn, H. Linander, L. Högberg, T. Persson, J. C. Escher, B. Lindquist

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 139 KB

english, 2003

9

A pharmacoscintigraphic evaluation of oral budesonide given as controlled-release (Entocort) capsules

S. Edsbäcker, B. Bengtsson, P. Larsson, P. Lundin, Å. Nilsson, J. Ulmius, P. Wollmer

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 260 KB

english, 2003

10

Pharmacokinetics of budesonide controlled-release capsules when taken with omeprazole

S. Edsbäcker, P. Larsson, M. Bergstrand

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 81 KB

english, 2003

11

Pharmacokinetics and systemic effects of inhaled fluticasone propionate in healthy subjects

L. Thorsson, K. Dahlström, S. Edsbäcker, A. Källén, J. Paulson, J-E. Wirén

Journal:

British Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 501 KB

english, 1997

12

Dose-proportional pharmacokinetics of budesonide inhaled via Turbuhaler®

Kaiser, Aaronson, Dockhorn, Edsbäcker, Korenblat, Källén

Journal:

British Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

13

Systemic availability of budesonide after nasal administration of three different formulations: pressurized aerosol, aqueous pump spray, and powder

Thorsson, Borgå, Edsbäcker

Journal:

British Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 111 KB

english, 1999

14

Rectal pharmacokinetics of budesonide

K. Dahlström, S. Edsbäcker, A. Källén

Journal:

European Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 581 KB

english, 1996

15

Pharmacokinetics of budesonide enema in patients with distal ulcerative colitis or proctitis

Å. DANIELSSON, S. EDSBÄCKER, R. LÖFBERG, Å. NILSSON, M. NYMAN-PANTELIDIS, O. OLSSON, O. SUHR, R. WILLÉN

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1993

Language:

english

File:

PDF, 469 KB

english, 1993

16

Nasal retention of budesonide and fluticasone in man: Formation of airway mucosal budesonide-esters in vivo

Hannes Petersen, Annika Kullberg, Staffan Edsbäcker, Lennart Greiff

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 82 KB

english, 2001

17

Evidence of the in vivo esterification of budesonide in human airways

Karen I. Maassen Van Den Brink, Martin Boorsma, A. Jeske Staal-van den Brekel, Staffam Edsbäcker, Emiel F. Wouters, Lars Thorsson

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 681 KB

english, 2008

18

Airway Selectivity: An Update of Pharmacokinetic Factors Affecting Local and Systemic Disposition of Inhaled Steroids

Staffan Edsbäcker, Carl-Johan Johansson

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2006

Language:

english

File:

PDF, 261 KB

english, 2006

19

Kinetics of the epimeric glucocorticoid budesonide

Ryrfeldt, Åke, Edsbäcker, Staffan, Pauwels, Romain

Journal:

Clinical Pharmacology & Therapeutics

Year:

1984

Language:

english

File:

PDF, 402 KB

english, 1984

20

In vitro biotransformation of glucocorticoids in liver and skin homogenate fraction from man, rat and hairless mouse

Paul Andersson, Staffan Edsbäcker, Åke Ryrfeldt, Christer von Bahr

Journal:

Journal of Steroid Biochemistry

Year:

1982

Language:

english

File:

PDF, 897 KB

english, 1982

21

Biotransformation rate (in vitro) and systemic potency (in vivo) of the topical glucocorticoid budesonide in male and female rats

Paul Andersson, Ralph Brattsand, Staffan Edsbäcker, Leif Källström, Åke Ryrfeldt

Journal:

Journal of Steroid Biochemistry

Year:

1982

Language:

english

File:

PDF, 449 KB

english, 1982

22

Do airway clearance mechanisms influence the local and systemic effects of inhaled corticosteroids?

Staffan Edsbäcker, Per Wollmer, Olof Selroos, Lars Borgström, Bo Olsson, Jarl Ingelf

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2008

Language:

english

File:

PDF, 1.99 MB

english, 2008

23

Vasoconstriction after inhalation of budesonide: A study in the isolated and perfused rat lung

Pär Ewing, Åke Ryrfeldt, Carl-Olof Sjöberg, Paul Andersson, Staffan Edsbäcker, Per Gerde

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 253 KB

english, 2010

24

Fluticasone and asthma

Staffan Edsbäcker, Lars Thorsson

Journal:

Year:

2001

Language:

english

File:

PDF, 54 KB

english, 2001

25

Oral availability of fluticasone propionate [letter]

P Andersson, R Brattsand, K Dahlstrom, S Edsbacker

Journal:

British Journal of Clinical Pharmacology

Year:

1993

Language:

english

File:

PDF, 434 KB

english, 1993

26

Dose-proportional kinetics of budesonide controlled ileal release capsules

M Nilsson, S Edsbäcker, P Larsson, JE Wirén

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 153 KB

english, 1995

27

Tissue Distribution of Ciclesonide and Budesonide in Mice

Mars, U., Johansson, A., Evetovics, E., Sjolin, P., Miller-Larsson, A., Edsbacker, S.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

28

Systemic exposure and availability of orally administered budesonide capsules (Entocort® EC) vs methylprednisolone

S Edsbäcker, P Larsson, P Höglund

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 52 KB

english, 2002

29

Systemic availability of Rhinocort Aqua (budesonide) nasal spray: Importance of formulation and definition of delivered dose

O'Dowd, Liza, Thorsson, Lars, Edsbacker, Staffan

Journal:

Journal of Allergy and Clinical Immunology

Year:

2002

Language:

english

File:

PDF, 42 KB

english, 2002

30

The bioavailability and airway clearance of the steroid component of budesonide/formoterol and salmeterol/fluticasone after inhaled administration in patients with COPD and healthy subjects: a randomized controlled trial

Chris Dalby, Tomasz Polanowski, Thomas Larsson, Lars Borgström, Staffan Edsbäcker, Tim W Harrison

Journal:

Respiratory Research

Year:

2009

Language:

english

File:

PDF, 1009 KB

english, 2009

31

Pharmacological Factors that Influence the Choice of Inhaled Corticosteroids

Dr Staffan Edsbäcker

Journal:

Year:

1999

Language:

english

File:

PDF, 200 KB

english, 1999

32

Budesonide fatty-acid esterification: a novel mechanism prolonging binding to airway tissue. Review of available data

Edsbäcker, Staffan, Brattsand, Ralph

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2002

Language:

english

File:

PDF, 437 KB

english, 2002

33

149

Kolosenko, Iryna, Edsbäcker, Elin, Fryknäs, Mårten, Johnsson, Per, Grandér, Dan, Tamm, Katja Pokrovskaja, Lindera, Stig, Milito, Angelo De

Journal:

Year:

2013

Language:

english

File:

PDF, 38 KB

english, 2013

34

Budesonide controlled ileal release (CIR) capsules affect plasma cortisol less than prednisolone

Edsbäcker, S, Larsson, P, Nilsson, M, Wirén, JE

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 146 KB

english, 1995

35

Targeted delivery of oral budesonide (Entocort® capsules) in healthy volunteers and Crohn's disease patients

Lundin, Pal, Edsbacker, Staffan, Larsson, Per, Wollmer, Per

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

36

Tissue Accumulation Kinetics of Ciclesonide-active Metabolite and Budesonide in Mice

Mårs, Ulla, d'Argy, Roland, Hallbeck, Karin, Miller-Larsson, Anna, Edsbäcker, Staffan

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2013

Language:

english

File:

PDF, 615 KB

english, 2013

37

Once‐Daily Inhaled Budesonide for the Treatment of Asthma: Clinical Evidence and Pharmacokinetic Explanation

Selroos, Olof, Edsbäcker, Staffan, Hultquist, Christer

Journal:

Journal of Asthma

Year:

2004

Language:

english

File:

PDF, 451 KB

english, 2004

38

Gut delivery of budesonide, a locally active corticosteroid, from plain and controlled-release capsules

Edsbäcker, Staffan, Larsson, Per, Wollmer, Per

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

39

Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator AZD5423 after Inhalation in Healthy Volunteers

Werkström, V, Prothon, S, Ekholm, E., Jorup, C, Edsbäcker, S.

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2016

Language:

english

File:

PDF, 257 KB

english, 2016

40

Lung deposition of budesonide from Turbuhaler® is twice that from a pressurized metered-dose inhaler P-MDI

Thorsson, L., Edsbäcker, S., Conradson, T-B.

Journal:

European Respiratory Journal

Year:

1994

Language:

english

File:

PDF, 155 KB

english, 1994

41

Effect of food on budesonide pharmacokinetics in patients with active Crohnʼs disease

Naber, T. H.J., Jansen, J. B.M.J., Cvetkovic, S., Edsbacker, S., Persson, T.

Journal:

European Journal of Gastroenterology & Hepatology

Year:

1998

File:

PDF, 113 KB

1998

42

Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs

Kolosenko, Iryna, Fryknäs, Mårten, Forsberg, Sofi, Johnsson, Per, Cheon, HyeonJoo, Holvey-Bates, Elise G., Edsbäcker, Elin, Pellegrini, Paola, Rassoolzadeh, Hanif, Brnjic, Slavica, Larsson, Rolf, Star

Journal:

International Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 595 KB

english, 2015

43

Lung deposition of budesonide from a pressurized metered-dose inhaler attached to a spacer

Thorsson, L., Edsbäcker, S.

Journal:

European Respiratory Journal

Year:

1998

Language:

english

File:

PDF, 208 KB

english, 1998

44

Seasonal and geographic variations in the incidence of asthma exacerbations in the United States

Gerhardsson de Verdier, M., Gustafson, Per, McCrae, Christopher, Edsbäcker, Staffan, Johnston, Neil

Journal:

Journal of Asthma

Year:

2017

Language:

english

File:

PDF, 510 KB

english, 2017

45

Efficacy and Tolerability of an Inhaled Selective Glucocorticoid Receptor modulator - AZD5423 - in COPD Patients: Phase II Study Results

Kuna, Piotr, Aurivillius, Magnus, Jorup, Carin, Prothon, Susanne, Taib, Ziad, Edsbäcker, Staffan

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2017

Language:

english

File:

PDF, 774 KB

english, 2017

46

New techniques for studying airway drug pharmacokinetics for asthma therapeutics

Edsbäcker, Staffan

Journal:

Expert Review of Clinical Pharmacology

Year:

2017

Language:

english

File:

PDF, 638 KB

english, 2017

47

RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients

Kolosenko, Iryna, Edsbäcker, Elin, Björklund, Ann-Charlotte, Hamil, Alexander S., Goroshchuk, Oksana, Grandér, Dan, Dowdy, Steven F., Palm-Apergi, Caroline

Journal:

Journal of Controlled Release

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

48

Colds as predictors of the onset and severity of COPD exacerbations

Johnston, Neil, Olsson, Marita, Edsbäcker, Staffan, Gerhardsson de Verdier, Maria, Gustafson, Per, McCrae, Christopher, Coyle, Peter, McIvor, Andrew

Journal:

International Journal of Chronic Obstructive Pulmonary Disease

Year:

2017

Language:

english

File:

PDF, 781 KB

english, 2017

49

STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes

Edsbäcker, Elin, Serviss, Jason T., Kolosenko, Iryna, Palm-Apergi, Caroline, De Milito, Angelo, Tamm, Katja Pokrovskaja

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.21 MB

english, 2019